Leveraging a unique de-risking platform to develop anti-fibrotic and regenerative therapeutics.
Our drug development platform harnesses the amazing ability of reindeer antler skin to heal without scarring.
After healing, scarred skin remains itchy (due to impaired nerve regrowth), lacks mobility (due to limited stretch, elasticity and plasticity), lack of hair and glands (which help to regulate temperature through sweating), and psychological effects if the scar is in a visible location.
FibroDynamx discovery pipeline is based on reindeer antler skin’s remarkable ability to heal without scar. In the same animal an injury in the back skin leaves a scar (much like in humans). We have harnessed this amazing ability of the reindeer antler skin to identify and validate drug targets for therapies to prevent scarring from happening in the first place.
Improve healing
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Reduce scarring
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Improve healing — Reduce scarring —
Who we are
We are a team of scientists and medical care professionals that believe improving treatments for patients to prevent scarring is a crucial unmet need.
Latest News
Fibroblast inflammatory priming determines regenerative versus fibrotic skin repair in reindeer
Single-cell multi-omics reveal that uninjured antler skin (velvet) fibroblasts resemble human fetal fibroblasts, whereas back skin fibroblasts express inflammatory mediators mimicking pro-fibrotic adult human and rodent fibroblasts. Consequently, injury elicits site-specific immune responses: back skin fibroblasts amplify myeloid infiltration and maturation during repair, whereas velvet fibroblasts adopt an immunosuppressive phenotype that restricts leukocyte recruitment and hastens immune resolution.
Reindeer represent a powerful comparative model for interrogating divergent wound healing outcomes, and our results nominate decoupling of fibroblast-immune interactions as a promising approach to mitigate scar.
